Plasma claudin-3 is associated with tumor necrosis factor-alpha-induced intestinal endotoxemia in liver disease.

ZhaoHan Wang,Aiyao Wang,Zhibin Gong,Ivano Biviano,Hui Liu,Jianfang Hu

Clinics and Research in Hepatology and Gastroenterology（2019）

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摘要

Plasma claudin-3, but not D-lactate, was found to be a marker of IP in patients with liver diseases. Elevated plasma TNF-α in such patients was likely to have injured the intestinal barrier, leading to IETM, especially in end-stage LC.

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关键词

Claudin-3,D-lactate,Intestinal endotoxemia,Liver cirrhosis,Tumor necrosis factor-alpha,Interferon gamma

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