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Omega-3 fatty acids are protective in hepatic ischemia reperfusion injury in the absence of GPR120 signaling.

Meredith A Baker,Prathima Nandivada, Paul D Mitchell,Gillian L Fell,Amy Pan,Bennet S Cho,Denis J De La Flor,Lorenzo Anez-Bustillos,Duy T Dao,Vania Nosé,Mark Puder

Journal of Pediatric Surgery（2019）

Cited 10|Views21
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Abstract
IV FO pretreatment was able to reduce HIRI in GPR120 KO mice, suggesting the hepatoprotective effects of FO are not mediated by GPR120 alone.
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ALT,ANOVA,CI,DHA,EPA,FO,GPR120,H&E,HIRI,IKKβ,IQR,IV,JNK,KO,NFκB,O3FA,RIPA,S,SEM,TAB1,TAK1,WT
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