Emergence of two novel recombinant porcine reproductive and respiratory syndrome viruses 2 (lineage 3) in Southwestern China.

Long Zhou,Runmin Kang,Yi Zhang,Jifeng Yu,Bo Xie,Changying Chen,Xingyu Li,Bin Chen,Luqi Liang,Jiawen Zhu,Yiming Tian,Xin Yang,Hongning Wang

Veterinary Microbiology（2019）

Cited 15|Views11

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Abstract

•The genomic characterization of two novel lineage 3 PRRSVs (GZgy17 and SCya18) was analyzed.•Multiple novel aa/nt deletions were observed within the genomes of GZgy17 and SCya18.•GZgy17 and SCya18 both originated from a lineage 3 strain and had recombined with lineage 8 and 1 strain, respectively.•GZgy17 exhibited higher pathogenicity in piglets compared to SCya18.

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Key words

Porcine reproductive and respiratory syndrome virus (PRRSV),ORF5,Lineage 3,Recombination,Pathogenicity

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