RGD peptide-decorated micelles assembled from polymer-paclitaxel conjugates towards gastric cancer therapy.
Colloids and Surfaces B: Biointerfaces(2019)
Abstract
•RGD-decorated PEG-PTX conjugate micelles with redox responsiveness have been developed.•PTX will be released from the otherwise stable micelles in response to intracellular GSH.•The micelles are tumor-targeting and can be used for gastric cancer therapy with high efficacy.
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Key words
Polymer-drug conjugates,RGD peptide,Tumor-targeting micelles,Drug release,Gastric cancer
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