Protective effects of Rosavin on bleomycin-induced pulmonary fibrosis via suppressing fibrotic and inflammatory signaling pathways in mice
Biomedicine & Pharmacotherapy(2019)
Abstract
•Rosavin could ameliorate Bulmonary fibrosis progression in bleomycin(BLM) in mice.•The expression levels of Nrf2, NF-κB p65, TGF-β1 and α-SMA were inhibited.•The mechanisms relies on the inflammatory response and antioxidative capacity.
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Key words
Rosavin,Bleomycin,Pulmonary fibrosis,Inflammatory response,Anti-oxidant
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