Optimal timing of hepatitis B virus DNA quantification and clinical predictors for higher viral load during pregnancy.

HBV DNA quantification should be performed before 22 weeks of gestation. Viral load cut-offs similar to those at 28 weeks can be used to determine immunoprophylaxis failure at earlier gestation. Maternal positive HBeAg status was associated with a higher chance of viral load >6 log IU/ml,7 log IU/ml or 8 log IU/ml. This article is protected by copyright. All rights reserved.