Photo-controlled delivery of a potent analogue of doxorubicin.
CHEMICAL COMMUNICATIONS(2019)
摘要
Highly cytotoxic agents have found an important niche in targeted anticancer therapy. Here we develop a new light release strategy for the targeting of one of these agents, 2-pyrrolinodoxorubicin, showing dramatic enhancements in toxicity with light and single digit nM potency.
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关键词
doxorubicin,potent analogue,photo-controlled
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