The C-DILI™ Assay: An Integrated In Vitro Approach to Predict Cholestatic Hepatotoxicity.
EXPERIMENTAL CHOLESTASIS RESEARCH（2019）
关键词
Adaptive response,BSEP—Bile salt export pump,Bile acid transport,Cholestatic hepatotoxicity,Compensatory mechanism,DILI—Drug-induced liver injury,FXR—Farnesoid X receptor,MRP—Multidrug resistance-associated protein,OST—Organic solute and steroid transporter,Primary hepatocyte culture,SCHH—Sandwich-cultured human hepatocytes,Transporter Certified™,efflux transport
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