Volumetric assessment of apparent diffusion coefficient predicts outcome following chemoradiation for cervical cancer

Jennifer C. Ho,Penny Fang,Carlos E. Cardenas,Abdallah S.R. Mohamed,Clifton D. Fuller,Pamela K. Allen,Priya R. Bhosale,Michael M. Frumovitz,Anuja Jhingran,Ann H. Klopp

Radiotherapy and Oncology（2019）

Cited 8|Views8

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Abstract

•90th% ADC of tumor on MRI significantly predicts PFS and DMFS in cervical cancer patients treated with CRT.•Overall survival, PFS, and DMFS were worse in patients with 90th percentile ADC < 1.917.•Patients with a low 90th percentile ADC value (<1.917), as well as a high MRI volume (>18.9 cm3) have the worst prognosis.

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Key words

Cervical cancer,Diffusion weighted imaging,Apparent diffusion coefficient,Chemoradiation

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