Association of single nucleotide polymorphisms at HSPB1 rs7459185 and TGFB1 rs11466353 with radiation esophagitis in lung cancer

Blas David Delgado,María Valle Enguix-Riego, Jon Cacicedo Fernández de Bobadilla,Daniel Herrero Rivera, Jose María Nieto-Guerrero Gómez,Juan Manuel Praena-Fernández,Eleonor Rivin del Campo, María José Ortiz Gordillo, María del Carmen Fernandez Fernandez,Jose Luis Lopez Guerra

Radiotherapy and Oncology（2019）

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摘要

•The rs7459185CC genotype predicts acute radiation-induced esophageal toxicity in lung cancer.•The rs11466353TT/TG genotypes predict late radiation-induced esophageal toxicity in lung cancer.•Genetic analysis with radiation dosimetric factors might be used in personalized RT.

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关键词

Single nucleotide polymorphisms,HSPB1,TGFB1,Radiation esophagitis,Lung cancer

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