Neurocan is a New Substrate for the ADAMTS12 Metalloprotease: Potential Implications in Neuropathies.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology（2019）
Abstract
Overall, our results suggest that ADAMTS12 could be involved in the repair of the CNS through its ability to degrade neurocan. Moreover, it can be inferred that alterations in neurocan degradation processes could be associated with the pathogenesis of neurological disorders.
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Key words
ADAMTS,Extracellular matrix,Metalloprotease,Neurocan,Neurocanase
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