Mesenchymal stem cell therapy inhibited inflammatory and profibrotic pathways induced by partial bladder outlet obstruction and prevented high-pressure urine storage.
Journal of Pediatric Urology（2019）
Abstract
Partial bladder outlet obstruction induced significant upregulation of hypoxic, inflammatory, and profibrotic markers. Mesenchymal stem cell therapy potently inhibited these pathways and improved bladder function.
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Key words
Mesenchymal stem cell therapy,Partial bladder outlet obstruction,Anti-inflammatory,Anti-fibrotic,Hypoxia
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