Computed tomography-guided percutaneous cryoablation for lung ground-glass opacity: A pilot study.

CONTEXT:Ground-glass opacity (GGO) is a nonspecific imaging parameter for early-stage pulmonary cancer. In these cases, a definite diagnosis and prompt surgery usually yield satisfactory outcomes. AIMS:This study aimed to assess the safety and feasibility of cryoablation treatment for lung GGO. SUBJECTS AND METHODS:We reviewed the clinical data of 14 patients (19 lung tumors) with lung GGO and evaluated the adverse events, lung function, and treatment efficacy after cryoablation. STATISTICAL ANALYSIS USED:Statistical analyses were performed using the Statistical Package for the Social Sciences software (version 13.0; SPSS Inc., Chicago, IL, USA). RESULTS:None of the patients exhibited serious complications, and lung function recovered to >95% after 1 month. During a follow-up, computed tomography scan at 24 months, the GGO appeared to have been successfully ablated in all patients. CONCLUSION:Cryoablation may serve as a safe and feasible option for the treatment of GGO.