Escherichia coli harboring in a cluster of liver transplant recipients: detection through active surveillance and whole genome sequencing.

Nenad Macesic,Sabrina Khan,Marla J Giddins,Daniel E Freedberg,Susan Whittier,Daniel A Green,E Yoko Furuya,Elizabeth C Verna,Medini K Annavajhala,Angela Gomez-Simmonds,Anne-Catrin Uhlemann

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY（2019）

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摘要

mcr-1, a plasmid-associated gene for colistin resistance, was first described in China in 2015, but its spread in the United States is unknown. We report detection of mcr-1-carrying Escherichia coil ST117 in a cluster of three liver transplant recipients.

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关键词

antimicrobial resistance,colistin,mcr-1,polymyxin B,whole-genome sequencing

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