High intensity interval training improves physical performance in aged female mice: a comparison of mouse frailty assessment tools.

•HIIT, 10-min, 3-days-a-week for 8 weeks increases performance in aged female mice.•Excellent agreement between the three Fried phenotype based mouse frailty tools.•The deficit accumulation tool was the only one to discern greater frailty with age.•None of the frailty assessment tools correlated with underlying pathology.•All tools distinguished or trended toward distinguishing mortality in mice..