Evaluating minimal important differences and responder definitions for the asthma symptom diary in patients with moderate to severe asthma.
Journal of patient-reported outcomes（2019）
摘要
The Asthma Symptom Diary was responsive to changes in clinical status in patients with moderate to severe asthma. Responder definitions were identified, including symptomatic days, for evaluating individual level treatment effects in clinical trials.
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关键词
Asthma,Asthma symptom diary,Interpretation guidelines,Minimal important difference,Responder definitions,Responsiveness to change
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