Change in patterns of failure after image-guided brachytherapy for cervical cancer: analysis from the RetroEMBRACE study.

Li-Tee Tan,Richard Pötter,Alina Sturdza,Lars Fokdal,Christine Haie-Meder,Maximilian Schmid, Deborah Gregory,Primoz Petric,Ina Jürgenliemk-Schulz,Charles Gillham,Eric Van Limbergen,Peter Hoskin,Ekkasit Tharavichitkul,Elena Villafranca,Umesh Mahantshetty,Christian Kirisits,Jacob Lindegaard,Kathrin Kirchheiner,Kari Tanderup

International Journal of Radiation Oncology*Biology*Physics（2019）

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摘要

Implementation of IGABT has changed the patterns of relapse after chemo-radiotherapy for cervical cancer. The predominant failure of after IGABT is systemic while the predominant failure with conventional brachytherapy is pelvic. Effective treatments to eradicate micro-metastases in PAN and distant organs are needed in addition to IGABT and chemo-radiotherapy to maximize local, regional, PAN and systemic control and improve survival.

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