Participant centred safety surveillance of health care workers receiving influenza vaccination.

P Cashman,S Moberley, K Chee, J Stephenson, S Chaverot, J Martinelli,T Gadsden, C Bateman-Steel,L Redwood,Z Howard,M J Ferson,D N Durrheim

Vaccine(2019)

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摘要
Following the introduction of mandatory influenza vaccination for staff working in high risk clinical areas in 2018, we conducted active surveillance for adverse events following immunisation utilising an automated online survey to vaccine recipients at three and 42 days post immunisation. Most participants 2285 (92%) agreed to participate; 515 (32%) staff reported any symptom and eight (1.6%) sought medical attention. The odds of having a reaction decreased with age by approximately 2% per year. The system was acceptable to staff, and the data demonstrated rates of reported symptoms within expected rates for influenza vaccines from clinical trials. Rates of medical attendance were similar to previous surveillance. Participant centred real-time safety surveillance proved useful in this staff influenza vaccination context, providing reassurance with expected rates and profile of common adverse events following staff influenza vaccination.
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