A novel linear 3-O-methylated galactan isolated from Cantharellus cibarius activates macrophages.

Carbohydrate Polymers(2019)

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摘要
•A novel linear 3-O-methylated galactan (WCCP-N-b) from C. cibarius was identified.•WCCP-N-b increased phagocytosis and secretion of NO, TNF-α, IL-6 and IL-1β.•WCCP-N-b activated macrophages through Akt/NF-κB, MAPKs via TLR2 receptor.•The molecular weight of WCCP-N-b impacted the activation.
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关键词
Cantharellus cibarius,Polysaccharide,3-O-methylated galactan,Macrophage,TLR2
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