Discovery of 1,3-diphenyl-1H-pyrazole derivatives containing rhodanine-3-alkanoic acid groups as potential PTP1B inhibitors.
Bioorganic & Medicinal Chemistry Letters(2019)
摘要
Two series of the 1,3-diphenyl-1H-pyrazole derivatives containing rhodanine-3-alkanoic acid groups were identified as competitive protein tyrosine phosphatase 1B (PTP1B) inhibitors.
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关键词
PTP1B inhibitor,1,3-Diphenyl-1H-pyrazole,Rhodanine-3-alkanoic acid
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