Late-stage C–H amination of abietane diterpenoids
Organic & Biomolecular Chemistry(2019)
摘要
This study aims at highlighting the synthetic versatility of the rhodium-catalyzed C-H amination reactions using iodine(III) oxidants for the late-stage functionalization of natural products. Inter-and intramolecular nitrene insertions have been performed from various abietane diterpenoids, leading to the amination of the C-3, C-6, C-7, C-11 and C-15 positions. Ca. 20 aminated compounds have been isolated with yields of up to 86% and high levels of regio-, chemo-and stereoselectivities.
更多查看译文
关键词
abietane diterpenoids,amination,late-stage
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要