Microneedle array-based platforms for future theranostic applications.

Olivia Howells, Natasha Rajendran, Sarah Mcintyre, Sara Amini-Asl,Pauline Henri, Yufei Liu,Owen Guy,Anthony E G Cass,May C Morris,Sanjiv Sharma

CHEMBIOCHEM(2019)

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Abstract
Theranostics involves finding the biomarkers of a disease, fighting them through site specific drug delivery and following them for prognosis of the disease. Microneedle array technology has been used for drug delivery and extended for continuous monitoring of analytes present in the skin compartment. We envisage the use of microneedle arrays for future theranostic applications. The potential of combining microneedle array-based drug delivery and diagnostics as part of closed-loop control system for the management of diseases and delivery of precision drugs in individual patients is reported in this paper.
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Key words
artificial pancreas,microneedle arrays,theranostics,transdermal delivery
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