Comparative Study Of Core- And Surface-Radiolabeling Strategies For The Assembly Of Iron Oxide Nanoparticle-Based Theranostic Nanocomposites

This work highlights the superiority of the surface-radiolabeling strategy over the core-labeling strategy in the assembly of radioactive iron oxide nanoparticle (IONP)-based nanocomposites for use in multimodal imaging and targeted therapy. It also implies a possible overestimation of the labeling stability in previous studies and points out directions for further optimization.