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Cytotoxicity and Genotoxicity of a New Intracanal Medicament, 2-hydroxyisocaproic Acid-An In Vitro Study.

David Selis, Yashika Pande,Cristine Smoczer,Michelle Wheater,Jamal Alhabeil,Susan Paurazas,Mazin Askar

Journal of Endodontics（2019）

Cited 17|Views4
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Abstract
HICA is not cytotoxic and genotoxic at concentrations <10 mg/mL. At the concentration of 1 mg/mL, HICA is significantly less cytotoxic than calcium hydroxide.
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Key words
2-hydroxyisocaproic acid,cytotoxicity,DNA double-strand break,endodontic regeneration,genotoxicity
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