Treatment-related Death in Cancer Patients Treated with Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis

O. Abdel-Rahman,D. Helbling,J. Schmidt,U. Petrausch,A. Giryes,A. Mehrabi, O. Schöb,M. Mannhart,H. Oweira

Clinical Oncology（2017）

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摘要

•Meta-analysis of the risk of death associated with immune checkpoint inhibitors.•CTLA-4 inhibitors are associated with a higher risk of treatment-related death compared with control regimens.•The same is not true for PD-1 inhibitors.

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关键词

Atezolizumab,ipilimumab,nivolumab,pembrolizumab,treatment-related death,tremelimumab

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