Functional comparison of anoctamin 1 antagonists on human uterine smooth muscle contractility and excitability.
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi(2018)
Abstract
While all 3 ANO1 antagonists attenuate pregnant human uterine tissue contractility and excitability, BB is the most potent tocolytic drug. Our findings may serve as a foundation for future structure-function analyses for novel tocolytic drug development.
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Key words
ANO1,preterm labor,tocolytic
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