Identification of a new tadalafil analogue, N-3-hydroxypropylnortadalafil, in a supplement product.

Hui-Chun Lee,Yun-Lian Lin,Yen-Chun Huang,Chia-Fen Tsai,Der-Yuan Wang

Journal of Pharmaceutical and Biomedical Analysis（2018）

引用 11|浏览6

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摘要

•A new tadalafil analogue, N-3-hydroxypropylnortadalafil, was identified by NMR.•This analogue was adulterated in several supplement products from market.•This analogue can be distinguished with other isomers by different retention time.

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关键词

N-hydroxypropylnortadalafil,Tadalafil analogue,Adulterated food supplements,NMR

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