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Prenatal alcohol exposure reduces 5-HT concentration in mouse intestinal muscle and mucosa.

Katarzyna A Dylag,Sara V S Fidalgo,Paul R Gard,Bhavik Anil Patel

Environmental Toxicology and Pharmacology（2018）

Cited 5|Views14
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Abstract
•PAE resulted in decreased mucosal 5-HT in male and female offspring.•Decrease LMMP 5-HT was observed only in female offspring.•Tryptophan was found to be increased in mucosa and LMMP of female offspring only.•The results suggest a decreased synthesis of 5-HT due to PAE.
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Key words
5-HT,5HIAA,HPLC,LMMP
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