Validation Of A Novel Particle Isolation Procedure Using Particle Doped Tissue Samples

A novel particle isolation method for tissue samples was developed and tested using particle-doped peri-articular tissues from ovine cadavers. This enabled sensitivity of the isolation technique to be established by doping tissue samples of 0.25 g with very low particle volumes of 2.5 mu m(3) per sample. Image analysis was used to verify that the method caused no changes to particle size or morphologies. (C) 2018 The Authors. Published by Elsevier Inc.