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Clinical Results From The Theta Burst Versus High Frequency Repetitive Transcranial Magnetic Stimulation Effectiveness Evaluation In Depression (Three-D) Randomized Non-Inferiority Trial

Daniel M. Blumberger,Fidel Vila-Rodriguez,Kevin E. Thorpe,Kfir Feffer, Yoshihiro Nodaa,Peter Giacobbe,Yuliya Knyahnytska,Sidney H. Kennedy,Raymond W. Lam,Zafiris J. Daskalakis,Jonathan Downar

BIOLOGICAL PSYCHIATRY（2018）

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Abstract
Treatment-resistant major depressive disorder is common; repetitive transcranial magnetic stimulation (rTMS) using high frequency (10Hz) left-side dorsolateral prefrontal cortex (DLPFC) stimulation is an evidence-based treatment for this disorder. Intermittent theta burst stimulation (iTBS) is a newer form of rTMS that can be delivered in 3 min, versus 37.5 min for a standard 10Hz treatment session.
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Key words
Depression, rTMS, Theta Burst, Treatment Resistant Depression
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