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Concurrent treatment of aplastic anemia/Paroxysmal Nocturnal Hemoglobinuria syndrome with immunosuppressive therapy and eculizumab: a UK experience.

Morag Griffin,Austin Kulasekararaj,Sheyans Gandhi,Talha Munir,Stephen Richards,Louise Arnold,Nana Benson-Quarm,Nicola Copeland,Isabel Duggins,Kathryn Riley,Peter Hillmen,Judith Marsh,Anita Hill

HAEMATOLOGICA（2018）

Cited 22|Views12
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Abstract
Paroxysmal nocturnal hemoglobinuria (PNH), an ultra-orphan disease with a prevalence of 15.9 per million in Europe, is a life threatening disorder characterized by hemolysis, bone marrow failure and thrombosis. Patients with PNH prior to eculizumab had a median survival of between 10 and 22 years.[1
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Bone Marrow Failure,Immunosuppression,Paroxysmal Nocturnal Hemoglobinuria
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