Mechanosensitive ion channels in articular nociceptors drive mechanical allodynia in osteoarthritis.

B H He,M Christin,S Mouchbahani-Constance, A Davidova, R Sharif-Naeini

Osteoarthritis and Cartilage（2018）

引用 32|浏览5

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摘要

These results suggest that MSICs are sensitized during OA and directly contribute to mechanical allodynia. They therefore represent potential therapeutic targets in the treatment of OA pain.

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关键词

Pain,Osteoarthritis,Mono-iodoacetate,Mechanosensitive ion channel,Mechanotransduction,Patch-clamp

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