Characteristics and Prognostic Factors for Patients With HER2-overexpressing Breast Cancer and Brain Metastases in the Era of HER2-targeted Therapy: An Argument for Earlier Detection.

Clinical Breast Cancer(2018)

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摘要
Our finding supports the continued use of HER2-targeted therapy after BM diagnosis. In addition, future research on the clinical impact of detecting asymptomatic BM in patients with HER2 BC, in terms of improving prognosis, quality of life, and avoidance of whole brain radiotherapy, is warranted.
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关键词
Breast cancer epidemiology,Central nervous system metastasis,HER2-positive,Metastatic breast cancer,Prognosis
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