Direction of leukocyte polarization and migration by the phosphoinositide-transfer protein TIPE2

Svetlana A Fayngerts,Zhaojun Wang,Ali Zamani,Honghong Sun,Amanda E Boggs,Thomas P Porturas, Weidong Xie,Mei Lin,Terry Cathopoulis,Jason R Goldsmith,Anastassios Vourekas,Youhai H Chen

NATURE IMMUNOLOGY（2017）

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摘要

The polarization of leukocytes toward chemoattractants is essential for their directed migration. Chen and colleagues show that the phosphoinositide-transfer protein TIPE2 functions as a coordinator of leukocyte polarity.

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关键词

Chemokines,Chemotaxis,Biomedicine,general,Immunology,Infectious Diseases

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