Manifestations Of Lupus In The Kidney And How To Manage Them

Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE). Both the condition and its treatments are associated with considerable morbidity and mortality [1] with 33% of those with class IV disease reaching end-stage renal failure (ESRF) at 10 years [2]. However, earlier diagnosis and initiation of treatment are associated with better outcomes [3]. In this NDT Digest, we will discuss the classification of LN, the approaches to treatment based on guidelines and new evidence suggesting alternative strategies.