GW28-e0850 T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY(2017)

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摘要
Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function. The present study examined whether T-cad deficiency increases vascular vulnerability in T2DM. Vascular segments
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关键词
vascular vulnerability,t2dm,t-cadherin
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