GW28-e1134 CREG modulates Angiotensin II type 1 receptor to antagonize coronary oxidative stress and hypertension in salt-sensitive rats

Yujie Zhang,Xin Zhao,Chenghui Yan,Shaowei Liu,Nan Zhu,Xiaolin Zhang,Zhiming Zhu,Yaling Han,Wang Shuang

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2017）

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Abstract

This study examined whether CREG protected Sprague-Dawley (SD) rats against high salt-related hypertension and vascular endothelium oxidative stress, and explored the mechanisms and associated changes in components of the renin-angiotensin system and coronary artery injury.In this study, SD rats

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Key words

angiotensin,coronary oxidative stress,hypertension,oxidative stress,salt-sensitive

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