Reference intervals for serum bilirubin, urea, and uric acid in healthy Chinese geriatric population.

ObjectivesThe study aims to establish the reference intervals (RIs) for total bilirubin (TBIL), direct bilirubin (DBIL), urea (UR), and uric acid (UA) in healthy Chinese geriatric population. MethodsEight hundred and twenty cases from six representative geographical regions in China (including male 413 cases and female 407 cases) of apparently healthy individuals aged 60-96years were recruited. Serum TBIL, DBIL, UR, and UA were analyzed by automatic biochemical analyzer and RIs were determined following CLSI C28-A3 guidelines using a non-parametric method. ResultsIn apparently healthy Chinese geriatric population of China, the RIs of TBIL, DBIL, UR, and UA were 6.6 similar to 21.8mol/L, 1.9 similar to 8.0mol/L, 3.60 similar to 9.51mmol/L, 179.2 similar to 460.9mol/L in males and 6.1 similar to 20.0mol/L, 1.8 similar to 7.1mol/L,3.35 similar to 8.89mmol/L, 130.2 similar to 443.4mol/L in females, respectively. ConclusionsThe RIs of TBIL, DBIL, UR, and UA were established within apparently healthy geriatric Chinese population according to CLSIC28-A3 document, providing a reference for the clinical.