SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES

Sadia Naureen,Fatima Ijaz,Munawar Ali Munawar,Nadia Asif,Faryal Chaudhry,Muhammad Ashraf, Misbahul Ain Khan

JOURNAL OF THE CHILEAN CHEMICAL SOCIETY（2017）

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摘要

Indole-based tetraarylimidazoles were prepared by multicomponent reaction of substituted 2-arylindole-3-carbaldehydes, benzil, substituted anilines and ammonium acetate in acetic acid. The new compounds were evaluated for their antiurease and antioxidant activity. The synthesized compounds exhibited potent antiurease activity.

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关键词

Imidazole,Indole,antitumor,ammonium acetate

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