Cysteine protease cathepsin B mediates radiation-induced bystander effects

Yu Peng, Man Zhang,Lingjun Zheng,Qian Liang,Hanzeng Li,Jeng-Ting Chen,Hongyan Guo,Sawako Yoshina,Yu-Zen Chen,Xiang Zhao,Xiaoqi Wu,Bin Liu,Shohei Mitani,Jau-Song Yu,Ding Xue

NATURE（2017）

引用 69|浏览27

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摘要

The cysteine protease CPR-4, a cathepsin B homologue, is identified as a radiation-induced bystander effect (RIBE) factor in nematodes in response to ultraviolet or ionizing radiation, and causes inhibition of cell death and increased embryonic lethality.

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关键词

Cell death,Genetics,Radiotherapy,Risk factors,Science,Humanities and Social Sciences,multidisciplinary

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