Twelve Weeks Treatment Outcome Of Omega-3 Fatty Acid In Computer Vision Syndrome Dry Eye: An Open Label, Randomized, Controlled Pilot Study

BACKGROUNDThe incidence of Computer Vision Syndrome Dry Eye is on an increase. This study was targeted to evaluate the effect of Omega 3 Fatty Acids on this particular segment of population.METHODSA prospective, open label, randomized controlled trial was conducted on 67 male professional computer users aged 25-45 years who used computer for 8-10 hours a day. All the patients were subjected to OSDI questionnaire and patients with moderate-to-severe Dry Eye were included in the study. They were clinically monitored by TBUT, Rose Bengal Staining and Schirmer's 1 Test with anaesthesia on Day 1 and after 12 weeks of treatment. The patients were randomly divided into two groups. Group 1 (Prescribed only lubricant drops) consisted of 33 patients. Group 2 (Prescribed lubricant drops along with commercially available Omega 3 fatty acids with EPA 180 mg and DHA 120 mg 2 capsules a day for twelve weeks) consisted of 34 patients.RESULTSStatistical Software SPSS 21.0 was used to analyse the results. In Group 1, the mean OSDI, TBUT, RBS, Schirmer's Test parameters before treatment were 32.42 5.52, 6.25 1.32, 3.72 2.47, 6.03 1.40 and after treatment were 28.38 5.81, 7.06 2.03, 3.22 2.34, 6.53 1.61 respectively. Whereas in Group 2 before treatment they were 33.09 5.89, 5.26 1.56, 4.24 2.43, 5.62 1.58 and after treatment were 14.76 6.59, 9.12 1.47, 0.88 1.04, 9.15 1.65 respectively.CONCLUSIONThe comparison of the scores of two Groups revealed an undeniably positive role of Omega 3 Fatty Acids in Dry Eye of Computer Vision Syndrome.