Increased admission serum cold-inducible RNA-binding protein concentration is associated with prognosis of severe acute pancreatitis

•Serum CIRP levels are elevated after acute pancreatitis.•Serum CIRP levels are associated with disease severity.•CIRP in serum is an independent predictor for mortality, local complications and organ failure.•CIRP levels have high predictive value for mortality, local complications and organ failure.•CRIP levels have high discriminatory ability for severe acute pancreatitis.