Preoperative radiation dose escalation for rectal cancer using a concomitant boost strategy improves tumor downstaging without increasing toxicity: A matched-pair analysis.

Jillian R Gunther,Awalpreet S Chadha,Ui Sup Shin,In Ja Park,Kiran V Kattepogu,Jonathan D Grant,David C Weksberg,Cathy Eng,Scott E Kopetz,Prajnan Das,Marc E Delclos,Harmeet Kaur,Dipen M Maru,John M Skibber,Miguel A Rodriguez-Bigas,Y Nancy You,Sunil Krishnan,George J Chang

Advances in Radiation Oncology（2017）

Cited 16|Views38

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Abstract

CRT dose escalation for patients with LARC is safe and effective. The improved T-downstaging and local control observed in CB patients should encourage further dose escalation studies.

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Key words

Neoadjuvant Therapy,Adjuvant Chemotherapy

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