MP54-16 SURVIVAL ANALYSIS OF PATIENTS WITH MUSCLE INVASIVE BLADDER CANCER NOT SUITABLE FOR TREATMENT WITH A CURATIVE INTENT

You have accessJournal of UrologyBladder Cancer: Invasive IV1 Apr 2017MP54-16 SURVIVAL ANALYSIS OF PATIENTS WITH MUSCLE INVASIVE BLADDER CANCER NOT SUITABLE FOR TREATMENT WITH A CURATIVE INTENT Félix Guerrero Ramos, Santiago Pérez Cadavid, Angel Tejido Sánchez, Esther García Rojo, Daniel Antonio González Padilla, Raquel Sopeña Sutil, Felipe Villacampa Aubá, José Manuel Duarte Ojeda, Federico de la Rosa Kehrmann, and Juan Passas Martínez Félix Guerrero RamosFélix Guerrero Ramos More articles by this author , Santiago Pérez CadavidSantiago Pérez Cadavid More articles by this author , Angel Tejido SánchezAngel Tejido Sánchez More articles by this author , Esther García RojoEsther García Rojo More articles by this author , Daniel Antonio González PadillaDaniel Antonio González Padilla More articles by this author , Raquel Sopeña SutilRaquel Sopeña Sutil More articles by this author , Felipe Villacampa AubáFelipe Villacampa Aubá More articles by this author , José Manuel Duarte OjedaJosé Manuel Duarte Ojeda More articles by this author , Federico de la Rosa KehrmannFederico de la Rosa Kehrmann More articles by this author , and Juan Passas MartínezJuan Passas Martínez More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.1688AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Bladder cancer is the ninth most commonly diagnosed cancer worldwide, with more than 300,000 new cases per year, and it causes around 150,000 deaths every year. Despite these figures, there is scarce data in the literature on the prognosis of patients with muscle invasive bladder cancer (MIBC) who are unfit for curative treatment. Our aim is to find out the survival of patients diagnosed with MIBC who were not suitable for treatment with curative intent in our center. We also analyze variables associated with survival, as well as the number of visits to the emergency room and palliative procedures needed. METHODS Retrospective analysis of a cohort of patients with histopathologic diagnosis of MIBC dismissed for treatment with curative intent (cystectomy, radiotherapy and/or chemotherapy), between January 2007 and December 2012. We analyzed overall survival (OS) and cancer-specific survival (CSS), as well as their relationship with demographic (age, gender) and clinical/pathological variables (comorbidities, tumor stage, reason for dismissing curative treatment and urinary tract obstruction at diagnosis). We also evaluated the number of visits to the emergency room due to bladder cancer and palliative procedures needed: hemostatic transurethral resection (TUR), radiotherapy or nephrostomy catheter. RESULTS We included 110 patients (96 males/14 females), with a mean age of 79. Regarding American Society of Anesthesiologists (ASA) risk, 67.3% of them were ASA III or higher; 63.6% presented with localized stage and 21.8% with metastases at diagnosis. Around half of our patients (50.9%) had urinary tract obstruction at diagnosis. The main causes to dismiss treatment with curative intent were comorbidities (39.1%) and advanced stage (36.4%). OS at 1 and 2 years was 30% and 14% respectively, with a median OS of 7.17 months. CSS at 1 and 2 years was 50% and 28% respectively, with a median CSS of 12.1 months. Variables associated with a worse survival were advanced clinical stage and urinary tract obstruction. Patients attended the emergency room a mean of 2.85 times due to their cancer. In our series, 18.2% of the patients underwent hemostatic TUR, whilst 10% needed hemostatic radiotherapy and nephrostomy catheters were placed in 24.5% of them. CONCLUSIONS In our series we find out an OS under 2 years in most of the patients, with a median OS under 1 year. Factors associated with worse prognosis were the presence of urinary tract obstruction at diagnosis and advanced clinical stage. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e728 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Félix Guerrero Ramos More articles by this author Santiago Pérez Cadavid More articles by this author Angel Tejido Sánchez More articles by this author Esther García Rojo More articles by this author Daniel Antonio González Padilla More articles by this author Raquel Sopeña Sutil More articles by this author Felipe Villacampa Aubá More articles by this author José Manuel Duarte Ojeda More articles by this author Federico de la Rosa Kehrmann More articles by this author Juan Passas Martínez More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...