Multi-Institutional Prospective Study To Explore The Efficacy Of Oral Nutritional Supplements For The Patients Undergoing Gastrectomy Against Gastric Cancer (Ccog1301)

e15039 Background: Gastrectomy with lymphadenectomy and adjuvant chemotherapy is one of standards for treatment of gastric cancer (GC). Postoperative malnutrition is deemed inevitable, however, and there is paucity of evidence for effective nutritional intervention. A prospective trial was conducted to evaluate the efficacy of postoperative oral nutritional supplements (ONS). Methods: Stage I~III GC patients with BMI less than 25 who undergo distal or total gastrectomy received oral administration of Racol NF (Otsuka Pharmaceutical Factory, Japan), a liquid enteral nutritional formula, as a supplement to regular meals. Racol at a recommended dose of 400 kcal/400 ml per a day was started within 7 days postoperatively and was continued for 3 postoperative months. Data on treatment compliance were collected through a questionnaire filled-in by the patients. Primary end point was ratio of the body weight loss (BWL) at 3 months postoperatively. Secondary end points were the compliance of Racol and changes in b...