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Anti-inflammatory effects of phenolic-rich cranberry bean (Phaseolus vulgaris L.) extracts and enhanced cellular antioxidant enzyme activities in Caco-2 cells

Peter X. Chen,Hua Zhang,Massimo F. Marcone,K. P. Pauls,Ronghua Liu,Yao Tang,Bing Zhang,Justin B. Renaud,Rong Tsao

Journal of Functional Foods（2017）

Cited 35|Views22
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Abstract
•Abundance of flavonoids in regular-darkening (RR) cranberry bean extract.•RR extract displayed strong dose-dependent cellular antioxidant activity.•Regular- and non-darkening cranberry bean extract suppressed IL-8 secretion.•Both extract also enhanced antioxidant enzyme activity.
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Key words
Dry beans,Phaseolus vulgaris L.,Phenolic acids,Flavonoids,Anthocyanins,Proanthocyanidins,Antioxidant,Anti-inflammation,HPLC-DAD,LC-ESI-MS,Caco-2 cells
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