PM193 Possible Relation Between Syncope-Induced Rise of Brain Injury Markers and Clotting Disturbances During Positive Head-Up Tilt Test in Patients With Vasovagal Syndrome

Primary headache syndromes and chronic pain syndromes are common in patients with postural tachycardia syndrome (POTS). There is overlap in potential mechanisms for migraine, chronic pain, and POTS symptomatology. Management of chronic pain and headaches in POTS requires a judicious use of pharmacotherapies that takes into account patient comorbidities and co-existing symptoms. Patient-centric, non-pharmacologic modalities include physical exercise, cognitive behavioral therapies, and treatment of sleep disorders.