Gender and age effects on risk factor-based prediction of coronary artery calcium in symptomatic patients: A Euro-CCAD study

•Coronary artery calcification (CAC) prevalence among females lagged males by around 10 years.•Age, dyslipidaemia, hypertension, diabetes and smoking were independently predictive of CAC presence in both genders.•The most important predictors were dyslipidaemia and diabetes in males and diabetes and smoking in females.•There was no difference in the predictive ability of these risk factors between genders in patients aged ≤70 years.•In males aged >70 only dyslipidaemia predicted CAC presence, while in females only smoking and diabetes were predictive.