TNF-α Induces a Pro-Inflammatory Phenotypic Shift in Monocytes through ACSL1: Relevance to Metabolic Inflammation.

Fatema Al-Rashed,Zunair Ahmad,Mina Amin Iskandar,Jaakko Tuomilehto,Fahd Al-Mulla,Rasheed Ahmad

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology（2019）

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摘要

Our findings provide an evidence that TNF-α-associated inflammatory polarization in monocytes is an ACSL1 dependent process, which indicates its central role in TNF-α-driven metabolic inflammation.

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关键词

ACSL1,CD11c,Inflammation,Monocytes,TNF-α

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