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MicroRNA-575 regulates development of gastric cancer by targeting PTEN.

Ya-Nan Wang,Fang Xu,Pei Zhang,Pan Wang,Ya-Ning Wei,Chen Wu,Shu-Jie Cheng

Biomedicine & Pharmacotherapy（2019）

Cited 37|Views12
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Abstract
•We firstly showed miR-575 exerts a tumorigenic effect in the development of GC.•PTEN is validated to be a downstream target gene of miR-575.•miR-575-exerted effect is partially via regulating PTEN expression in the GC.
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Key words
Gastric cancer,microRNA-575,PTEN,Proliferation,Apoptosis
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